Who may be at risk from high dietary oxalates even if they don't have a very leaky gut?

Those with a history of heavy antibiotic use or recent antibiotic use may be at much greater risk from dietary oxalate. Many antibiotics can kill back the flora that degrades oxalate, including lactobacillus acidophilus and bifidus. These bacteria that comprise the main ingredients in most probiotics may have been taken with the idea they would discourage yeast. It is a very good idea to try and replenish these familiar commensal bacterias , but they are just so-so at degrading oxalate because they really prefer other foods. That is not the case with another bacteria, which is an anaerobe called oxalobacter formigenes. Oxalobacter cannot survive without eating up oxalate, so oxalate makes it happy and makes it grow. Several studies have shown that those who develop oxalate-related disease generally lack oxalobacter in their stool.